The reference site for Guanfacine

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WHAT IS GUANFACINE?

Guanfacine is an oral, centrally-acting, alpha2-adrenergic receptor agonist used alone or in combination with other drugs for the treatment of hypertension (high blood pressure).

It works by producing a decrease in sympathetic outflow, resulting in a reduction in peripheral vascular resistance, renal vascular resistance, heart rate, and blood pressure.

Guanfacine is similar to clonidine but is more selective for alpha2-adrenergic receptors, longer acting, dosed once daily, and has less frequency and severity of rebound hypertension following abrupt discontinuation.

 

Brand Name(s): Tenex
CAS nº: 29110-47-2
(GWAHN fa seen)

 

Product Info

The sections below will provide you with more specific information and guidelines related to fluoxetine and its correct use. Please read them carefully.

FDA Information

Guanfacine was approved by the Food and Drug Administration in 1986. A prescription is required for this medicine.

Please visit the official site of the FDA for further information.

Why is this medication prescribed?

Guanfacine is an oral medication that belongs to the general class of medicines called antihypertensives. It is used to treat high blood pressure (hypertension).

High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Guanfacine works by controlling nerve impulses along certain nerve pathways. As a result, it produces a decrease in sympathetic outflow, resulting in a reduction in peripheral vascular resistance, renal vascular resistance, heart rate, and blood pressure.

Guanfacine is similar to clonidine but is more selective for alpha2-adrenergic receptors, longer acting, dosed once daily, and has less frequency and severity of rebound hypertension following abrupt discontinuation.

Other uses for this medicine

Guanfacine is also sometimes prescribed for Attention Deficit/Hyperactivity Disorder (AD/HD).

However, it is important that you talk to your doctor about the possible risks of using this drug for your particular condition.

Dosage and using this medicine

Guanfacine comes as a tablet to be taken orally.

Take guanfacine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Each dose should be taken with a full glass of water. Additionally, take guanfacine at bedtime unless otherwise directed by your doctor. This medication may make you drowsy and may cause some dizziness. Taking it at bedtime may help to prevent falls and injuries.

Do not stop taking this medication suddenly even if you feel better. Taking this medication regularly is important in the treatment of your condition.

What special precautions should I follow?

BEFORE TAKING GUANFACINE:

Tell your doctor if you have any type of heart disease, had a heart attack, stroke, kidney disease, or liver disease. You may need a lower dose or special monitoring during treatment with guanfacine if you have any of the conditions listed above.

Moreover, do not take other drugs such as sleeping pills, prescription pain relievers, antihistamines, or antidepressants without first talking to your doctor. These medicines may increase the drowsiness caused by guanfacine. You should also inform your doctor or pharmacist about any other prescription or over-the-counter medications you are taking.

Guanfacine is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Furthermore, it is not known whether guanfacine passes into breast milk and how it might affect a nursing infant. Do not take this medicine without first talking to your doctor if you are pregnant or breast-feeding a baby.

If you are over 60 years of age, you may be more likely to experience side effects from guanfacine therapy. You may require a lower dose.

The FDA has not approved guanfacine for use by children younger than 12 years of age.

Use cautiously when driving, operating machinery, or performing other hazardous activities. Guanfacine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Additionally, try to avoid alcohol while taking guanfacine, as it may increase the drowsiness you experience from guanfacine therapy and may also increase dizziness.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose.

Do not take a double dose of this medication.

What side effects can this medication cause?

If you experience any of the following serious side effects, stop taking guanfacine and seek emergency medical attention:

an allergic reaction (difficulty breathing, closing of your throat, swelling of your lips, tongue, or face, or hives)
a very slow heart rate (fewer than 60 beats per minute)
unusually high or low blood pressure (fainting, a severe headache, flushing of your face)

Other, less serious side effects may be more likely to occur. Continue to take guanfacine and talk to your doctor if you experience any of the following:

unusual fatigue, dizziness, or tiredness
headache
constipation, nausea, vomiting, or diarrhea
insomnia
dry mouth (sucking on ice chips or sugarless hard candy may relieve this side effect)

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Always keep this medication in the container it came in, tightly closed, and out of reach of children. Store at room temperature and away from excess heat and moisture (not in the bathroom).

Remeber to throw away any medication that is outdated or no longer needed. Should you have any doubts, talk to your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose

In the case of an overdose, call your local poison control center on 1-800-222-1222. However, if the victim has collapsed or is not breathing, please call the local emergency services on 911.

Symptoms of overdose may include:

drowsiness
a sluggish feeling
weakness
lightheadedness
a slow heart rate
nausea
vomiting
possibly seizures

Product Images

PICTURES OF GUANFACINE PILLS

Below you will find images and specific information on the principal types of guanfacine that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

 

Name: GUANFACINE
Strength(s): 1 MG
Imprint: WATSON 444
Manufacturer: WATSON LABS.

Name: GUANFACINE
Strength(s): 1 MG
Imprint: G | GU1
Manufacturer: PAR PHARM.

Name: TENEX®
Strength(s): 1 MG
Imprint: TENEX | 1 AHR
Manufacturer: ESP PHARM.

Name: TENEX®
Strength(s): 1 MG
Imprint: 1 AHR
Manufacturer: A.H. ROBINS PHARM.

Name: GUANFACINE
Strength(s): 2 MG
Imprint: WATSON 453
Manufacturer: WATSON LABS.

Name: GUANFACINE
Strength(s): 2 MG
Imprint: M | G5
Manufacturer: MYLAN

Name: TENEX®
Strength(s): 2 MG
Imprint: TENEX | 2 AHR
Manufacturer: ESP PHARM.

Name: TENEX®
Strength(s): 2 MG
Imprint: 2AHR
Manufacturer: A.H. ROBINS PHARM.

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